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The Bison is a high throughput instrument capable of imaging high density arrays of simultaneous reactions, using the popular microwell plate format.
Designed by Flying Pixel. ERBA Molecular is currently exploring a number of technical solutions for the splitting bispn samples to enable automated detection of multiple pathogens in parallel.
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The instrument is available for research applications and development collaborators for external development activities. It is anticipated that with this approach a much more cost effective, fully integrated device with a pathway to CLIA waivability is achievable in the near term. Both instruments have low manufacturing cost as there are no expensive thermocyclers or optical components and no moving parts. Our experience can mean that the instrument development for new product release is no longer a bisoh hurdle and systems can be rapidly brought to market.
Digital BART has the potential to transfer these research applications into routine diagnostic procedures by dramatically reducing the cost and complexity of associated instrumentation.
The portable nature of the instrument makes it ideally suited for use in decentralised settings in clinical and non-clinical applications. The reduction in the chemistry complexity has enabled the early stage development of much simpler, fully integrated devices.
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The PDQ is straight-forward to boson, easy to use, low maintenance and can be battery operated. The Bison shares many of the simplicity and cost benefits of the PDQ whilst being configured to read a much higher number of samples. If you are interested in any of these solutions then please contact us via This email address is being protected from spambots.
Prior to the acquistion by ERBA Mannheim, Lumora has developed and commercialised two versions of hardware to perform mdx; a small ccs PDQ that can run samples at a time or a high throughput platform Bison that can run 96 — samples and image down to a nL. ERBA Molecular approach to molecular diagnostic assay development has focused on simplifying the work flow by reducing the complexity of the chemistry.
This will offer significant benefits in areas such as respiratory infections and sexual health screens.
Underneath its casing bisin PDQ platform consists of a heater block for isothermal reactions and an array of “off-the-shelf” photodiodes for real-time bioluminescent reading, making it incredibly robust yet keeping the manufacturing cost remarkably low.
The PDQ is probably the simplest ever instrument for closed tube, real-time amplification and detection assays.
In addition, this digital camera based system has also been used with well plates in proof-of-concept studies for Digital BART. It’s used for screening primers for inclusivity, exclusivity and general performance characteristics.
In addition, we are adapting the image sensing Bison platform to concepts for digital analysis, which will enable absolute quantification in applications such as rare mutation detection and copy number analysis.