Fast, reproducible application switching Quick Select Feature recalls up to three saved amplifier configurations. Flexible Selectable command sensitivity for flexible control of the output waveform. Easy monitoring of membrane and cell health parameters Integrated seal test in voltage- and current-clamp mode. Specifications General Specifications Dimensions in. Major new features of the MultiClamp B Amplifier include Internal Automatic Mode switching, triggered by external signals or the recording itself; Oscillation Suppression for better cell protection; and Slow Current Injection to compensate for drifting potentials.
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This ensures that the amplifier settings are accurately and conveniently stored in the recorded data files.
Molecular Devices MultiClamp 700B Amplifier
A critical part of drug discovery involves safety assessments, such as hERG testing, in order to eliminate any compounds with potential safety concerns. Ion channels are pore proteins that are involved in a large variety of physiological processes. Basic research in the ion channel field furthers the understanding of ion channel function as well as their roles within cellular pathways and processes. Series resistance compensation Correction improves the bandwidth of the recording by eliminating the error introduced by the voltage drop across the series resistance.
Audio monitor for acoustic tracking of the signal while you are busy looking down a microscope. Automated optimization features; reduction of manipulation steps; and convenient; reliable telegraphing. Prediction helps achieve the desired multilamp level faster by transiently supercharging the membrane potential.
Whole-cell and multiclwmp patch clamp recordings are typically used to investigate the action of modulators on entire populations of ion channels in the membrane of a cell. Selectable output gain with 11 settings to scale the output signal to the desired level.
Ion channels play a role in many diseases, including hypertension, cardiac arrhythmias, gastrointestinal, immune and neuromuscular disorders, pathological pain and cancer.
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Easy monitoring of membrane and cell health mu,ticlamp Integrated seal test in voltage- and current-clamp mode. Quick Select provides easy access to stored preset configurations that apply to particular applications. Request a quote or view related items.
Fast, reproducible application switching Quick Select Feature recalls up to three saved amplifier configurations. Specifications General Specifications Dimensions in. Automatic pipette capacitance compensation requires only the push of a button to neutralize the contribution of the glass pipette and the pipette holder to the capacitance of the circuitry.
Computer control of the amplifier ensures correct scaling and logging of experimental parameters. Products Electrophysiology Rigs Other Required Components Amplifiers and DAQ Amplifiers Molecular Devices MultiClamp B Amplifier A microelectrode amplifier that combines leading edge electronics design and a wealth of features and functions with an intuitive user interface that simplifies the creation of complex protocols. Automatic mode switching enables you to control the transition between voltage and current clamp by an external trigger or depending on the recorded signal.
Drug Ejection Pressure Ejection. Applications Ion channels are pore proteins that are involved in a large variety of physiological processes. Flexible Selectable command sensitivity for flexible control of the output waveform.
Fine tunable 4-pole bessel and butterworth low-pass filters act as anti-aliasing filters and can be used to pre-condition the output signal. At Scientifica we take your privacy seriously and will only use your personal information to provide the products and umlticlamp you have requested from us.
A microelectrode amplifier that combines leading edge electronics design and a wealth of features and functions with an intuitive user multiclzmp that simplifies the creation of complex protocols.
Software control of all amplifier settings Automated optimization features; reduction of manipulation steps; and convenient; reliable telegraphing.
Axon™ MultiClamp™ Commander Software Download page
For single-channel recordings, whole-cell voltage- and current-clamp recordings, intracellular sharp electrode recordings, extracellular field potential recordings in ion channel, neuroscience, nanopore and voltammetry studies.
Rack use Standard 19″ rack-mount 2U with handles. Conventional patch clamp has played an important role in collecting evidence for the absence of side effects before submission of a drug candidate to regulatory authorities. If you consent to us collecting and storing your data from this form please tick the checkbox below. Even if automated electrophysiology has shifted safety testing to earlier stages in the drug discovery multoclamp, follow-up with conventional patch clamp is an essential step in the workflow.
Automatic correction Leak subtraction for automatic correction of leak currents with a smart, 70b algorithm.
Learn more Safety Assessment A critical part of drug discovery involves safety assessments, such mjlticlamp hERG testing, in order to eliminate any compounds with potential safety concerns. To order the Multiclamp B amplifier please Call us at: